Azathioprine

硫唑嘌呤

Report date: 2026/04/28 20:00:22
NME

Base Information

Drug NameAzathioprine
Drug Alias NameAzatioprina硝基咪唑硫嘌呤Azathioprinum氮杂硫代嘌呤脒唑硫嘌呤 +[18] 
ClassificationSmall molecules > Heterocyclic drugs
Mechanisms of ActionHypoxanthine-guanine phosphoribosyltransferase inhibitors
TargetsHypoxanthine-guanine phosphoribosyltransferase
Therapy Area/IndicationsRejection of organ transplantationRejection of renal transplantationUlcerative proctitis +[26] 
Global Approved IndicationsRejection of organ transplantationRejection of renal transplantationUlcerative proctitis +[24] 
Approved Indications in ChinaRejection of organ transplantationAutoimmune DiseasesHyperthyroidism +[12] 
Original Approved Country/TerritoryUnited States
Original Approved Date1968/03/20
Country/TerritoryUnited StatesUnited KingdomEU +[5] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaApproved
Originator CompaniesSebela Ireland Ltd
China Registration ClassN/A

Develop Information

Active CompaniesSandozFuji Pharma Co LtdLipomed Gmbh +[6] 
Inactive CompaniesN/A
Active IndicationsRejection of organ transplantationRejection of renal transplantationUlcerative proctitis +[26] 
Inactive IndicationsN/A

Other Information

ATC CodeL04AX01
Related LinksWikipediaDrugBankKEGG