Pregnenolone

N/A

Report date: 2026/03/17 20:00:15
NME

Base Information

Drug NamePregnenolone
Drug Alias NameneurosteroidNBI-113
ClassificationSmall molecules > Steroids
Mechanisms of ActionGABA-A receptor; benzodiazepine site agonistsAcetylcholinesterase inhibitorsDopamine receptors antagonists +[4] 
TargetsGABA-A receptor; benzodiazepine siteGlutamate [NMDA] receptorDopamine receptors +[4] 
Therapy Area/IndicationsMenopausal symptomsStress Disorders, Post-TraumaticSchizophrenia +[11] 
Global Approved IndicationsN/A
Approved Indications in ChinaN/A
Original Approved Country/TerritoryN/A
Original Approved DateN/A
Country/TerritoryUnited StatesSingapore
CombinationsNo
Global Highest StatusPhase 2 Clinical
Highest Status in ChinaN/A
Originator CompaniesNeurocrine Biosciences Inc
China Registration ClassN/A

Develop Information

Active CompaniesUniversity of Texas Southwestern Medical CenterVa Office Of Research And DevelopmentYale University +[4] 
Inactive CompaniesSingapore Clinical Research InstituteDuke UniversityNational University Of Singapore
Active IndicationsMenopausal symptomsAutistic DisorderAutism Spectrum Disorder +[9] 
Inactive IndicationsStress Disorders, Post-TraumaticSchizophrenia

Other Information

ATC CodeN/A
Related LinksWikipediaDrugBankKEGG