Glycerol phenylbutyrate

苯丁酸甘油酯

Report date: 2025/12/23 17:51:12
NME

Base Information

Drug NameGlycerol phenylbutyrate
Drug Alias Name苯基丁酸甘油酯glyceroli phenylbutyrasGlyceryl tri-(4-phenylbutyrate)甘油苯丁酸酯fenilbutirato de glicerol +[9] 
ClassificationSmall molecules > Heterocyclic drugs
Mechanisms of ActionAmmonia scavengers
TargetsNot applicable
Therapy Area/IndicationsDevelopmental and epileptic encephalopathyCorticobasal degenerationNeurodevelopmental Disorders +[10] 
Global Approved IndicationsUrea Cycle Disorders, Inborn
Approved Indications in ChinaUrea Cycle Disorders, Inborn
Original Approved Country/TerritoryUnited States
Original Approved Date2013/02/01
Country/TerritoryCanadaUnited StatesUkraine +[7] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaApproved
Originator CompaniesHyperion Therapeutics Inc
China Registration ClassN/A

Develop Information

Active CompaniesHorizon TherapeuticsOrphanpacificWeill Medical College of Cornell University +[7] 
Inactive CompaniesColumbia UniversityUniversity Of Colorado DenverAmgen Inc
Active IndicationsDevelopmental and epileptic encephalopathyCorticobasal degenerationNeurodevelopmental Disorders +[5] 
Inactive IndicationsDrug-Related Side Effects and Adverse ReactionsColor Vision DefectsParkinson Disease +[5] 

Other Information

ATC CodeA16AX09
Related LinksWikipediaDrugBankKEGG