Isotretinoin

异维甲酸

Report date: 2026/04/21 20:00:18
NME

Base Information

Drug NameIsotretinoin
Drug Alias Name异维A酸13-CRA13-cis-Retinoic acidEpurisSotret +[20] 
ClassificationSmall molecules
Mechanisms of ActionRetinoic acid receptors agonists
TargetsRetinoic acid receptors
Therapy Area/IndicationsCoronavirus Disease 2019 (COVID-19)Skin UlcerRosacea +[16] 
Global Approved IndicationsAcne Vulgaris
Approved Indications in ChinaAcne Vulgaris
Original Approved Country/TerritoryUnited States
Original Approved DateN/A
Country/TerritoryCanadaUnited StatesPuerto Rico +[15] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaApproved
Originator CompaniesF. Hoffmann-La Roche Ltd
China Registration ClassN/A

Develop Information

Active CompaniesGlaxosmithkline Uk LtdF. Hoffmann-La Roche LtdSouth Valley University +[7] 
Inactive CompaniesGlaxosmithkline PlcF. Hoffmann-La Roche AgShahid Beheshti University Of Medical Sciences +[19] 
Active IndicationsMelanosisAcne VulgarisOligospermia +[5] 
Inactive IndicationsCoronavirus Disease 2019 (COVID-19)Skin UlcerRosacea +[11] 

Other Information

ATC CodeD10AD04D10BA01
Related LinksWikipediaDrugBankKEGG