Cilastatin Sodium/Imipenem

西司他丁钠/亚胺培南

Report date: 2022/01/14 13:23:58

Base Information

Drug NameCilastatin Sodium/Imipenem
Drug Alias Name西司他丁钠和亚胺培南Imipenem hydrate-cilastatin sodium mixtImipenem hydrate-cilastatin sodium西司他丁钠•亚胺培南西司他丁/亚胺培南 +[15] 
ClassificationSmall molecules > Heterocyclic drugs > Antibiotics > β-lactam antibiotics > Carbapenems antibiotics
Mechanisms of ActionBacterial penicillin-binding protein inhibitorsEnzymes inhibitors
TargetsEnzymesBacterial penicillin-binding protein
Therapy Area/IndicationsLower Respiratory Tract InfectionsAcute bacterial skin and skin structure infectionsEndocarditis +[10] 
Global Approved IndicationsLower Respiratory Tract InfectionsAcute bacterial skin and skin structure infectionsEndocarditis +[10] 
Approved Indications in ChinaBacterial Infections
Original Approved Country/TerritoryGermany
Original Approved Date1984/01/01
Country/TerritoryUnited StatesGermanyEgypt +[5] 
CombinationsYes Cilastatin SodiumImipenem
Global Highest StatusApproved
Highest Status in ChinaApproved
Originator CompaniesMerck Sharp & Dohme Corp
China Registration ClassN/A

Develop Information

Active CompaniesMerck Sharp & Dohme CorpMerck & Co Inc
Inactive CompaniesAin Shams University
Active IndicationsLower Respiratory Tract InfectionsAcute bacterial skin and skin structure infectionsEndocarditis +[10] 
Inactive IndicationsN/A

Other Information

ATC CodeJ01DH51
Related LinksWikipediaKEGG