Miglustat

麦格司他

Report date: 2025/06/27 17:33:39
NMEFirst In Class

Base Information

Drug NameMiglustat
Drug Alias Name米鲁司他Miglustatum米格鲁特米格鲁司特美格鲁特 +[16] 
ClassificationSmall molecules > Heterocyclic drugs
Mechanisms of ActionCeramide glucosyltransferase inhibitorsAcidic alpha-glucosidase inhibitors
TargetsCeramide glucosyltransferaseAcidic alpha-glucosidase
Therapy Area/IndicationsGaucher's disease type IDiarrheaHypersensitivity +[12] 
Global Approved IndicationsNiemann-Pick DiseasesGaucher Disease
Approved Indications in ChinaNiemann-Pick Diseases
Original Approved Country/TerritoryEU
Original Approved Date2002/11/20
Country/TerritoryBelgiumCanadaUnited States +[14] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaApproved
Originator CompaniesActelion Pharmaceuticals Ltd
China Registration ClassN/A

Develop Information

Active CompaniesJanssen-Cilag International NvAdvanz Pharma Holdco LtdAmicus Therapeutics Us Inc +[6] 
Inactive CompaniesChildren'S National Research InstituteCliniques Universitaires Saint-Luc A.S.B.L.University Of Florida +[7] 
Active IndicationsNiemann-Pick DiseasesGaucher DiseaseGlycogen Storage Disease Type II
Inactive IndicationsGaucher's disease type IDiarrheaHypersensitivity +[9] 

Other Information

ATC CodeA16AX06
Related LinksWikipediaDrugBankKEGG