Pegargiminase

培精氨酸酶

Report date: 2026/04/03 20:03:44

Base Information

Drug NamePegargiminase
Drug Alias Name培阿吉酶Peglyated arginine deiminaseArginine deiminase-PEGPEG arginine deiminasePegylated arginine deiminase 20000 +[17] 
ClassificationBiologics > Protein drugs > Enzyme > Recombinant enzymeBiologics > Protein drugs > Recombinant protein > Recombinant enzyme
Mechanisms of ActionPeptidyl Arginine Deiminase replacements
TargetsPeptidyl Arginine Deiminase
Therapy Area/IndicationsUveal melanomaSkin MelanomaSolid tumours +[24] 
Global Approved IndicationsN/A
Approved Indications in ChinaN/A
Original Approved Country/TerritoryN/A
Original Approved DateN/A
Country/TerritoryBelgiumCanadaUnited States +[13] 
CombinationsNo
Global Highest StatusNDA/BLA
Highest Status in ChinaPhase 3 Clinical
Originator CompaniesPhoenix Pharmacologics Inc
China Registration ClassN/A

Develop Information

Active CompaniesPolaris Group Designerx Pharmaceuticals IncPolaris Group LtdWashington University School Of Medicine +[7] 
Inactive CompaniesPolaris Pharmaceuticals IncLudwig Institute For Cancer ResearchUniversity Of Miami +[5] 
Active IndicationsMetabolic Dysfunction-Associated Steatotic Liver DiseaseProstatic NeoplasmsSmall Cell Lung Carcinoma +[9] 
Inactive IndicationsUveal melanomaSkin MelanomaSolid tumours +[15] 

Other Information

ATC CodeN/A
Related LinksDrugBank