Tacrolimus Hydrate

他克莫司水合物

Report date: 2026/05/26 20:00:28
NME

Base Information

Drug NameTacrolimus Hydrate
Drug Alias Name藤霉素Tacrolimusum HydrateFujimycin HydrateProtopyGraceptor (as hydrate) +[25] 
ClassificationSmall molecules > Heterocyclic drugsSmall molecules > Molecular Glue
Mechanisms of ActionCalcineurin inhibitorsCytokines inhibitorsImmunosuppressants +[5] 
TargetsCalcineurinFK506-binding protein 1ACytokines +[4] 
Therapy Area/IndicationsRejection of pancreatic transplantationRejection of organ transplantationRejection of renal transplantation +[54] 
Global Approved IndicationsRejection of organ transplantationRejection of renal transplantationGraft vs Host Disease +[6] 
Approved Indications in ChinaRejection of organ transplantation
Original Approved Country/TerritoryUnited States
Original Approved Date1994/04/08
Country/TerritoryCzechiaBelgiumBulgaria +[38] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaApproved
Originator CompaniesAstellas Pharma Inc
China Registration ClassN/A

Develop Information

Active CompaniesAstellas Pharma Us IncEximore LtdShanghai Jiao Tong University School of Medicine +[20] 
Inactive CompaniesHeinrich Heine University DusseldorfSandozUniversity Of Medicine And Dentistry Of New Jersey +[34] 
Active IndicationsRejection of pancreatic transplantationRejection of organ transplantationRejection of renal transplantation +[34] 
Inactive IndicationsMedication AdherenceWounds and InjuriesEdema +[20] 

Other Information

ATC CodeD11AH01L04AD02
Related LinksWikipediaDrugBankKEGG