Buprenorphine Hydrochloride/Naloxone Hydrochloride

盐酸丁丙诺啡/盐酸纳洛酮

Report date: 2026/05/26 20:00:28

Base Information

Drug NameBuprenorphine Hydrochloride/Naloxone Hydrochloride
Drug Alias Name纳洛酮/丁丙诺啡Buprenorphine/Naloxone丁丙诺啡/纳洛酮Buprenorphine - naloxone mixtbuprenorphine + naloxone （Insys） +[14] 
ClassificationSmall molecules
Mechanisms of ActionKappa opioid receptor antagonistsMu opioid receptor agonistsOpioid receptors antagonists
TargetsOpioid receptorsMu opioid receptorKappa opioid receptor
Therapy Area/IndicationsHeroin DependenceOpioid-Related Disorders
Global Approved IndicationsOpioid-Related Disorders
Approved Indications in ChinaOpioid-Related Disorders
Original Approved Country/TerritoryUnited States
Original Approved Date2002/10/08
Country/TerritoryCanadaUnited StatesEU +[4] 
CombinationsYes Buprenorphine HydrochlorideNaloxone Hydrochloride
Global Highest StatusApproved
Highest Status in ChinaApproved
Originator CompaniesIndivior PLC
China Registration ClassN/A

Develop Information

Active CompaniesEdenbridge Pharmaceuticals LlcIndivior Uk LtdIndivior Europe Ltd +[4] 
Inactive CompaniesThe University Of California DavisFriends Research Institute IncDuke University +[12] 
Active IndicationsOpioid-Related Disorders
Inactive IndicationsHeroin Dependence

Other Information

ATC CodeN07BC51
Related LinksWikipediaKEGG