Pegaspargase

培门冬酶

Report date: 2024/04/26 13:35:34

Base Information

Drug NamePegaspargase
Drug Alias NameAsparaginase macrogolLyophilised pegaspargasePEG-asparaginasePEG-L-asparaginasePegylated asparaginase +[10] 
ClassificationBiologics > Protein drugs > Enzyme > Recombinant enzymeBiologics > Protein drugs > Recombinant protein > Recombinant enzyme
Mechanisms of ActionAspartate-ammonia ligase inhibitorsAmidohydrolases stimulantsAsparagine inhibitors
TargetsAspartate-ammonia ligaseAmidohydrolasesAsparagine
Therapy Area/IndicationsFallopian Tube NeoplasmsOvarian NeoplasmsPeritoneal Neoplasms +[6] 
Global Approved IndicationsPrecursor Cell Lymphoblastic Leukemia-LymphomaNeoplasms
Approved Indications in ChinaNeoplasms
Original Approved Country/TerritoryUnited States
Original Approved Date1994/02/01
Country/TerritoryUnited StatesNetherlandsGermany +[7] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaApproved
Originator CompaniesEnzon Pharmaceuticals IncSigma-Tau SpaLaboratoires Servier +[4] 
China Registration ClassN/A

Develop Information

Active CompaniesShireSigma-Tau SpaSun Yat-Sen University +[4] 
Inactive CompaniesAdir SarlInstitut De Recherches Internationales ServierNational Cancer Institute +[4] 
Active IndicationsLymphoma, Extranodal NK-T-CellPrecursor Cell Lymphoblastic Leukemia-LymphomaNeoplasms
Inactive IndicationsFallopian Tube NeoplasmsOvarian NeoplasmsPeritoneal Neoplasms

Other Information

ATC CodeL01XX24
Related LinksWikipedia