Methotrexate Sodium

甲氨蝶呤钠

Report date: 2023/11/02 20:01:30
NME

Base Information

Drug NameMethotrexate Sodium
Drug Alias NameIntradose-MTXFarmitrexatAmethopterin (sodium salt)G-301MPI-5004 +[7] 
ClassificationSmall molecules > Heterocyclic drugs
Mechanisms of ActionDihydrofolate reductase inhibitors
TargetsDihydrofolate reductase
Therapy Area/IndicationsCoronavirus Disease 2019 (COVID-19)Polyarticular Juvenile Idiopathic ArthritisPsoriasis +[16] 
Global Approved IndicationsPsoriasisCrohn DiseaseArthritis, Rheumatoid +[12] 
Approved Indications in ChinaN/A
Original Approved Country/TerritoryUnited States
Original Approved Date1959/08/10
Country/TerritoryUnited StatesBrazilIndia +[4] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaN/A
Originator CompaniesEndo International Plc
China Registration ClassN/A

Develop Information

Active CompaniesNordic Group BvHospira IncAzurity Pharmaceuticals Inc
Inactive CompaniesAzidus BrasilStrides Pharma International AgAmneal Pharmaceuticals Llc +[4] 
Active IndicationsPsoriasisCrohn DiseaseArthritis, Rheumatoid +[13] 
Inactive IndicationsCoronavirus Disease 2019 (COVID-19)Polyarticular Juvenile Idiopathic ArthritisLymphoma, Non-Hodgkin

Other Information

ATC CodeL01BA01L04AX03
Related LinksWikipediaDrugBankKEGG