Sodium Phenylbutyrate/Tauroursodeoxycholic acid (Amylyx Pharmaceuticals)

苯基丁酸钠/牛磺脱氧胆酸 (Amylyx Pharmaceuticals)

Report date: 2026/04/08 15:31:50

Base Information

Drug NameSodium Phenylbutyrate/Tauroursodeoxycholic acid (Amylyx Pharmaceuticals)
Drug Alias NameTauroursodeoxycholic Acid/Sodium Phenylbutyrate (Amylyx Pharmaceuticals)牛磺脱氧胆酸/苯基丁酸钠Phenylbutyric acid sodium/Tauroursodeoxycholic acid (Amylyx Pharmaceuticals)Tauroursodeoxycholic acid/Phenylbutyric acid sodium (Amylyx Pharmaceuticals)Sodium phenylbutyrate/Taurursodiol (Amylyx Pharmaceuticals) +[10] 
ClassificationSmall molecules > SteroidsSmall molecules > Heterocyclic drugs
Mechanisms of ActionHistone deacetylase inhibitorsG-protein coupled bile acid receptor 1 agonists
TargetsHistone deacetylaseG-protein coupled bile acid receptor 1
Therapy Area/IndicationsNeurodegenerative DiseasesAmyotrophic Lateral SclerosisAlzheimer Disease +[6] 
Global Approved IndicationsAmyotrophic Lateral Sclerosis
Approved Indications in ChinaN/A
Original Approved Country/TerritoryCanada
Original Approved Date2022/06/10
Country/TerritoryBelgiumCanadaUnited States +[14] 
CombinationsYes Sodium PhenylbutyrateUrsodoxicoltaurine
Global Highest StatusNDA/BLA
Highest Status in ChinaN/A
Originator CompaniesAmylyx Pharmaceuticals Inc
China Registration ClassN/A

Develop Information

Active CompaniesNeopharmAmylyx Pharmaceuticals Inc
Inactive CompaniesN/A
Active IndicationsNeurodegenerative DiseasesAmyotrophic Lateral SclerosisSupranuclear Palsy, Progressive +[5] 
Inactive IndicationsAlzheimer Disease

Other Information

ATC CodeN/A
Related LinksN/A