Trazodone Hydrochloride

盐酸曲唑酮

Report date: 2022/01/14 13:23:58
NME

Base Information

Drug NameTrazodone Hydrochloride
Drug Alias NameTrazodona Hydrochloride曲唑酮盐酸盐Trazodonum HydrochlorideTrazadone HydrochlorideMolipaxin +[10] 
ClassificationSmall molecules > Heterocyclic drugs
Mechanisms of ActionSerotonin transporter inhibitorsSerotonin reuptake inhibitorsSerotonin 1a (5-HT1a) receptor antagonists +[5] 
TargetsSerotonin transporterSerotonin 1a (5-HT1a) receptorSerotonin 2c (5-HT2c) receptor +[4] 
Therapy Area/IndicationsDepressive Disorder, MajorAnxiety DisordersSleep +[15] 
Global Approved IndicationsDepression
Approved Indications in ChinaDepression
Original Approved Country/TerritoryUnited States
Original Approved Date1981/12/24
Country/TerritoryCzechiaCanadaUnited States +[14] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaApproved
Originator CompaniesPragma Pharmaceuticals Llc
China Registration ClassN/A

Develop Information

Active CompaniesKamat Pharmatech LLCThe Brigham and Women's HospitalJohns Hopkins University +[7] 
Inactive CompaniesTargeted Medical PharmaLee'S Pharmaceutical LtdUniversidade Federal Do Paraná +[10] 
Active IndicationsDepressive Disorder, MajorDepressionHypertension +[9] 
Inactive IndicationsAnxiety DisordersSleepOpioid-Related Disorders +[6] 

Other Information

ATC CodeN06AX05
Related LinksWikipediaDrugBankKEGG