Melphalan Flufenamide

N/A

Report date: 2024/03/05 17:50:44
NME

Base Information

Drug NameMelphalan Flufenamide
Drug Alias Name美法仑氟芬胺melphalanum flufenamidumMelflufen氟美法仑melphalan flufenamide hydrochloride +[9] 
ClassificationSmall molecules > Synthetic peptide > Peptide drug conjugate (PDC)
Mechanisms of ActionAlkylating agents
TargetsDNAAminopeptidase
Therapy Area/IndicationsUveal melanomaSkin MelanomaImmunologic Deficiency Syndromes +[25] 
Global Approved IndicationsMultiple Myeloma
Approved Indications in ChinaN/A
Original Approved Country/TerritoryUnited States
Original Approved Date2021/02/26
Country/TerritoryCzechiaBelgiumBulgaria +[28] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaN/A
Originator CompaniesOncopeptides Ab
China Registration ClassN/A

Develop Information

Active CompaniesOncopeptides Ab
Inactive CompaniesNational Institutes Of Health Clinical Center (Cc)Delcath Systems IncFate Therapeutics Inc +[8] 
Active IndicationsMultiple Myeloma
Inactive IndicationsUveal melanomaSkin MelanomaImmunologic Deficiency Syndromes +[24] 

Other Information

ATC CodeL01XX
Related LinksWikipediaDrugBankKEGG